Early hormone replacement therapy may yield benefits, researchers say

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Evaluation of the benefits and risks of hormone replacement therapy.

OBJECTIVE To review recent data on outcome of hormone replacement therapy in postmenopausal women. DATA SOURCES Medline search of the literature and local data. STUDY SELECTION Data on efficacy of hormone replacement and its unwanted side effects were examined. DATA EXTRACTION Statistical data were extracted from published studies and meta-analyses. DATA SYNTHESIS Statistical data came ...

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Hormone replacement therapy benefits meibomian gland dysfunction in perimenopausal women

Meibomian gland dysfunction (MGD) is believed to be the leading cause of dry eye (DE) disease worldwide. The connection between aging and MGD has long been recognized. However, few studies have addressed the relationship between MGD and hormone replacement therapy (HRT) in perimenopausal women, and not have examined the prevalence of MGD in perimenopausal women. The purpose of this study was to...

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Risks and benefits of hormone replacement therapy: the evidence speaks.

Until recently, observational studies suggested a decreased risk of cardiovascular disease, osteoporotic fractures, cognitive decline and colon cancer with the use of hormone replacement therapy (HRT). Recent randomized controlled trials have failed to show a protective effect of HRT in reducing the risk of coronary artery disease and instead have revealed an increased risk of heart disease, st...

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ژورنال

عنوان ژورنال: Canadian Medical Association Journal

سال: 2011

ISSN: 0820-3946,1488-2329

DOI: 10.1503/cmaj.109-4041